Beclometasone Impurity 33 CAS CATO-C4X-147433
| CAS No. | CATO-C4X-147433 |
| Molecular Formula | C22H28Cl2O4 |
| Molecular Weight | 427.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Beclometasone Impurity 33 (CAS CATO-C4X-147433, C22H28Cl2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Beclometasone Impurity 33 (C22H28Cl2O4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Beclometasone Impurity 33 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H28Cl2O4 |
| Molecular Weight | 427.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Beclometasone Standards
- Beclometasone Dipropionate Monohydrate EP Impurity U (CAS 79578-39-5)
- Beclometasone Dipropionate Monohydrate EP Impurity V (CAS 205105-83-5)
- Beclometasone Impurity 28 (CAS CATO-C4X-147428)
- Beclometasone Impurity 35 (CAS CATO-C4X-147435)
- Beclometasone Impurity 46 (CAS CATO-C4X-147446)
- Beclometasone Impurity 45 (CAS 34542-51-3)
- Beclometasone Impurity 47 (CAS CATO-C4X-147447)
- Beclometasone Impurity 44 (CAS 18769-20-5)
Recommended Standards
- Meclorisone (CAS 4732-48-3)
- Mometasone Impurity 28 (CAS CATO-C4X-170428)
- DCPIB (CAS 82749-70-0)
- Mometasone Furoate EP Impurity G (CAS 105102-22-5)
- Nabumetone Impurity 28 (CAS 98386-83-5)
- Pentoxyverine Impurity 16 (CAS CATO-C4X-227016)
- Letermovir Impurity 83 (CAS CATO-C4X-291583)
- Methyl 5-(aminomethyl)-2-methylfuran-3-carboxylate hydrochloride (CAS 1172939-55-7)
- N-(3,4-Dimethylphenyl)propionamide (CAS 22835-89-8)
- 2-Penten-1-ol, 1-acetate, (2Z)- (CAS 42125-10-0)
- 3-Ethyl-3-propylbenzofuran-2(3H)-one (CAS 742080-04-2)
- 2-(Pyridin-3-yloxy)propanoic acid (CAS 347186-55-4)
- 4-Aminobenzenesulfonyl Fluoride (CAS 98-62-4)
- CBP501 Affinity Peptide trifluoroacetate salt (CAS 1351804-17-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com