Mometasone Furoate EP Impurity K CAS 4647-20-5
| CAS No. | 4647-20-5 |
| Molecular Formula | C22H29ClO5 |
| Molecular Weight | 408.92 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Mometasone Furoate EP Impurity K (CAS 4647-20-5) is a certified pharmaceutical impurity reference standard with the molecular formula C22H29ClO5 and a molecular weight of 408.92 g/mol.
Based on its molecular formula C22H29ClO5, Mometasone Furoate EP Impurity K contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 408.92 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H29ClO5 |
| Molecular Weight | 408.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
Related Mometasone Standards
- Mometasone Furoate Impurity 25 (CAS CATO-C4X-170425)
- Mometasone EP Impurity M (CAS 57780-86-6)
- Mometasone Furoate EP Impurity Q (CAS 83881-08-7)
- Mometasone Impurity 28 (CAS CATO-C4X-170428)
- Mometasone Furoate EP Impurity G (CAS 105102-22-5)
- Mometasone Impurity 50 (CAS 23776-75-2)
- Mometasone Impurity 51 (CAS CATO-C4X-170451)
- Mometasone Impurity C13 (CAS 151265-36-0)
Recommended Standards
- Beclometasone Impurity 47 (CAS CATO-C4X-147447)
- Beclomethasone (CAS 4419-39-0)
- Beclomethasone (CAS CATO-C4X-147422)
- 2,2'-(5-Bromo-1,3-phenylene)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) (CAS 1150561-62-8)
- Fexofenadine Impurity 14 (CAS CATO-C4X-179414)
- Vortioxetine Impurity 77 (CAS 88-61-9)
- Dexamethasone Impurity 19 (CAS CATO-C4X-116519)
- 4-Bromo-3-nitrobenzoic acid methyl ester (CAS 2363-16-8)
- 2-(Piperidin-1-ylsulfonyl)ethan-1-amine (CAS 31644-46-9)
- (1-cyclobutylethyl)(methyl)amine (CAS 1427379-17-6)
- 2-Amino-6-(hydroxymethyl)-8-oxo-4-(m-tolyl)-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile (CAS 876710-04-2)
- (1-Benzhydryl-2-methylazetidin-3-yl)methanol (CAS 2231673-88-2)
- Ethyl 6-bromo-4-oxo-3,4-dihydroquinazoline-2-carboxylate (CAS 926273-65-6)
- Myelin Basic Protein (85-99) Peptide Antagonist (CAS 444305-16-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com