Betamethasone impurity 103 CAS CATO-C4X-1437103
| CAS No. | CATO-C4X-1437103 |
| Molecular Formula | C22H30FO8P |
| Molecular Weight | 472.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Betamethasone impurity 103.
Betamethasone impurity 103 (CAS CATO-C4X-1437103) is a certified pharmaceutical impurity reference standard with the molecular formula C22H30FO8P and a molecular weight of 472.44 g/mol.
The molecular framework of Betamethasone impurity 103 (C22H30FO8P) is characterized by a flavonoid core, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Betamethasone impurity 103 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H30FO8P |
| Molecular Weight | 472.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Betamethasone Standards
- Betamethasone Impurity 132 (CAS CATO-C4X-1437132)
- Betamethasone Impurity 135 (CAS CATO-C4X-1437135)
- Betamethasone impurity 45 (CAS 1215899-29-8)
- Betamethasone impurity 55 (CAS 1202002-02-5)
- Betamethasone impurity 56 (CAS 1202002-00-3)
- Betamethasone impurity 96 (CAS CATO-C4X-143796)
- Betamethasone Unknown Impurity 3 (CAS CATO-CPS-2303001)
- Betamethasone Acetate EP Impurity C (CAS 330157-05-6)
Recommended Standards
- Dexamethasone impurity 65 (CAS 1202002-01-4)
- Dexamethasone impurity 64 (CAS CATO-C4X-116564)
- Dexamethasone impurity 63 (CAS 1202001-99-7)
- D-Homo B Derivative of Dexamethasone (CAS CATO-C4X-116552)
- Fenticonazole Impurity 7 (CAS CATO-C4X-24917)
- Rimegepant Impurity 150 (CAS CATO-C4X-2487150)
- Amorolfine Impurity 91 (CAS CATO-C4X-154291)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com