Everolimus EP Impurity B CAS 1062122-63-7

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.1062122-63-7
Molecular FormulaC53H83NO14
Molecular Weight958.22 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Everolimus EP Impurity B CAS 1062122-63-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 958.22 g/mol gives Everolimus EP Impurity B distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Everolimus EP Impurity B (CAS 1062122-63-7) is a certified pharmaceutical impurity reference standard with the molecular formula C53H83NO14 and a molecular weight of 958.22 g/mol.

Structurally, Everolimus EP Impurity B (C53H83NO14) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 958.22 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Everolimus EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC53H83NO14
Molecular Weight958.22 g/mol
Purity>95%
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1988
Nitrogen Atoms1

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