Everolimus impurity 4 CAS CATO-C4X-11224
| CAS No. | CATO-C4X-11224 |
| Molecular Formula | C53H83NO14 |
| Molecular Weight | 958.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Everolimus impurity 4.
Everolimus impurity 4 (CAS CATO-C4X-11224) is a certified pharmaceutical impurity reference standard with the molecular formula C53H83NO14 and a molecular weight of 958.22 g/mol.
The molecular framework of Everolimus impurity 4 (C53H83NO14) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Everolimus impurity 4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C53H83NO14 |
| Molecular Weight | 958.22 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Everolimus Standards
- Everolimus EP Impurity B (CAS 1062122-63-7)
- Everolimus Ring-Opening Impurity (Mixture of Isomers) (CAS 1708118-13-1)
- Everolimus Impurity 33 (CAS 908340-97-6)
- Everolimus Impurity 36 (CAS 2402744-97-0)
- Everolimus Impurity 47 (CAS CATO-C4X-112247)
- Everolimus Impurity 5 (CAS CATO-C4X-11225)
- Everolimus EP Impurity D (CAS 2760174-96-5)
- Everolimus (CAS 159351-69-6)
Recommended Standards
- [(3R)-1-[(2R,3R,4R,5R)-2-[[(3R)-2,2-Difluoro-3-hydroxytetradecanoyl]Amino]-5,6-Dihydroxy-1-Oxo-4-Phosphonooxyhexan-3-Yl]Oxy-1-Oxotetradecan-3-Yl] Tetradecanoate (CAS 132760-29-3)
- Bis(1H,1H,2H,2H-perfluorodecyl)disulfide (CAS 42977-21-9)
- Bis(2-heptadecyl-1H-imidazole-κN3)bis(octanoato-κO)nickel (CAS 68912-08-3)
- 3-(((2-(((2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ylidene)amino)ethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (CAS 30576-47-7)
- Itraconazole Impurity 85 (CAS CATO-C4X-149785)
- Elobixibat Impurity 27 (CAS CATO-C4X-283827)
- Allopurinol EP Impurity B (CAS 22407-20-1)
- Piperacillin Impurity 70 (Mixture of Diastereomers) (CAS CATO-C4X-173270)
- N-(4-BRomophenyl)-3-hydroxybenzamide (CAS 92905-58-3)
- 2-Fluorobenzenesulfonohydrazide (CAS 872848-12-9)
- Benzyl 6-hydroxy-3-azabicyclo[4.1.0]Heptane-3-carboxylate (CAS 1803566-24-6)
- methyl 1-(hydroxymethyl)cyclopropanecarboxylate (CAS 88157-42-0)
- 2-Amino-N-methyl-N-(o-tolyl)acetamide (CAS 1018632-41-1)
- Semaglutide-d5 (CAS CATO-C4X-2226153)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com