Everolimus Impurity 33 CAS 908340-97-6
| CAS No. | 908340-97-6 |
| Molecular Formula | C53H83NO14 |
| Molecular Weight | 958.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Everolimus Impurity 33 (C53H83NO14) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Everolimus Impurity 33 (CAS 908340-97-6, C53H83NO14) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Everolimus Impurity 33 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C53H83NO14 |
| Molecular Weight | 958.22 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
Related Everolimus Standards
- Everolimus EP Impurity B (CAS 1062122-63-7)
- Everolimus Ring-Opening Impurity (Mixture of Isomers) (CAS 1708118-13-1)
- Everolimus Impurity 36 (CAS 2402744-97-0)
- Everolimus impurity 4 (CAS CATO-C4X-11224)
- Everolimus Impurity 47 (CAS CATO-C4X-112247)
- Everolimus Impurity 5 (CAS CATO-C4X-11225)
- Everolimus EP Impurity D (CAS 2760174-96-5)
- Everolimus (CAS 159351-69-6)
Recommended Standards
- [(3R)-1-[(2R,3R,4R,5R)-2-[[(3R)-2,2-Difluoro-3-hydroxytetradecanoyl]Amino]-5,6-Dihydroxy-1-Oxo-4-Phosphonooxyhexan-3-Yl]Oxy-1-Oxotetradecan-3-Yl] Tetradecanoate (CAS 132760-29-3)
- Bis(2-heptadecyl-1H-imidazole-κN3)bis(octanoato-κO)nickel (CAS 68912-08-3)
- Tylosin 3-Acetate (CAS 63409-10-9)
- Red-CLA (CAS 886840-56-8)
- Omeprazole Impurity 44 (CAS CATO-C4X-125544)
- Articaine EP Impurity D (CAS CATO-C4X-19125)
- Levofloxacin Impurity 30 (CAS CATO-C4X-137130)
- 2-[2-(4-chloropyrido[2,3-d]pyrimidin-6-yl)ethynyl]cyclopentanol (CAS 2617368-84-8)
- 3-(Nicotinamido)benzoic acid (CAS 72733-84-7)
- Clobetasone 17-Butyrate (CAS 25122-57-0)
- Ezetimibe Impurity 3 (CAS CATO-C4X-10983)
- (E)-6,6'-Dibromo-[3,3'-biindolinylidene]-2,2'-dione (CAS 1351240-72-6)
- 4-Benzoylbenzoyl chloride (CAS 39148-58-8)
- Semaglutide Impurity 14(Discontinued,See CPTD788307 ) (CAS CATO-C4X-222614)
Why CATO?
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