Everolimus Impurity 5 CAS CATO-C4X-11225

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-11225
Molecular FormulaC53H83NO14
Molecular Weight958.22 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Everolimus Impurity 5 CAS CATO-C4X-11225 chemical structure

Description

Everolimus Impurity 5 (C53H83NO14) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

CATO supplies Everolimus Impurity 5 (CAS CATO-C4X-11225), a pharmacopoeial impurity reference standard (molecular formula C53H83NO14, MW 958.22 g/mol) used for the identification and quantification of trace impurities in APIs.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC53H83NO14
Molecular Weight958.22 g/mol
Purity97%+
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms1

Related Everolimus Standards

Recommended Standards

Why CATO?