Everolimus Ring-Opening Impurity (Mixture of Isomers) CAS 1708118-13-1

Purity >80%In StockPharmacopoeial Impurity Standards
CAS No.1708118-13-1
Molecular FormulaC53H83NO14
Molecular Weight958.22 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Everolimus Ring-Opening Impurity (Mixture of Isomers) CAS 1708118-13-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 958.22 g/mol gives Everolimus Ring-Opening Impurity (Mixture of Isomers) distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Everolimus Ring-Opening Impurity (Mixture of Isomers) (CAS 1708118-13-1) is a certified pharmaceutical impurity reference standard with the molecular formula C53H83NO14 and a molecular weight of 958.22 g/mol.

The molecular framework of Everolimus Ring-Opening Impurity (Mixture of Isomers) (C53H83NO14) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Everolimus Ring-Opening Impurity (Mixture of Isomers) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC53H83NO14
Molecular Weight958.22 g/mol
Purity>80%
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1994
Nitrogen Atoms1

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