Posaconazole Impurity 120 CAS CATO-C4X-1208120
| CAS No. | CATO-C4X-1208120 |
| Molecular Formula | C13H20N2O2 |
| Molecular Weight | 236.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Posaconazole Impurity 120.
Posaconazole Impurity 120 (CAS CATO-C4X-1208120) is a certified pharmaceutical impurity reference standard with the molecular formula C13H20N2O2 and a molecular weight of 236.31 g/mol.
The molecular framework of Posaconazole Impurity 120 (C13H20N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Posaconazole Impurity 120 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H20N2O2 |
| Molecular Weight | 236.31 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Posaconazole Standards
- Posaconazole Impurity 33 (CAS 170985-85-0)
- Posaconazole Impurity 143 (CAS 1428118-40-4)
- Posaconazole Impurity 144 (CAS 2243785-81-9)
- Posaconazole impurity 242 (CAS CATO-C4X-1208242)
- Posaconazole Impurity 84 (CAS 122151-32-0)
- Posaconazole Impurity 265 (CAS CATO-C4X-1208265)
- Posaconazole Impurity 145 (CAS CATO-C4X-1208145)
- Posaconazole Impurity 81 (CAS 165115-73-1)
Recommended Standards
- N-((4-amino-2-propylpyrimidin-5-yl)methyl)butyramide (CAS 725-46-2)
- Heptyl Salicylate (CAS 6259-77-4)
- 2-(2-Methoxy-phenyl)-2-morpholin-4-yl-ethylamine 2748AF 904806-00-4 C13H20N2O2 (CAS 904806-00-4)
- Buspirone Impurity 22 (CAS 223461-35-6)
- Penicillamine EP Impurity A (CAS 20902-45-8)
- Ertugliflozin impurity 64 (CAS CATO-C4X-301164)
- Arotinolol Impurity 14 (CAS 1701418-50-9)
- 6-Bromo-2-methyl-1H-indole-3-carbaldehyde (CAS 17826-07-2)
- 1-(2-Amino-3-chloro-5-methoxyphenyl)ethanone (CAS 801235-15-4)
- 1-bromo-2-(2-butoxyethoxy)benzene (CAS 1249279-08-0)
- 3,5-Diphenyl-1H-pyrrole-2-carboxylic acid (CAS 100784-98-3)
- 4-(Difluoromethyl)-6-methoxy-5-(trifluoromethoxy)nicotinaldehyde (CAS 1804648-99-4)
- 1-(5-fluoro-1-benzofuran-2-yl)ethan-1-amine hydrochloride (CAS 1795283-85-0)
- Semaglutide Impurity 158 (x TFA Salt) (CAS CATO-C4X-2226158)
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