Losartan alpha-Butyl-Losartan Aldehyde Adduct CAS 1159977-48-6
| CAS No. | 1159977-48-6 |
| Molecular Formula | C44H44Cl2N12O2 |
| Molecular Weight | 843.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Losartan alpha-Butyl-Losartan Aldehyde Adduct (CAS 1159977-48-6), a certified reference material (molecular formula C44H44Cl2N12O2, MW 843.81 g/mol) for analytical method development and quality control.
The molecular framework of Losartan alpha-Butyl-Losartan Aldehyde Adduct (C44H44Cl2N12O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C44H44Cl2N12O2 |
| Molecular Weight | 843.81 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 28.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 12 |
Related Losartan Standards
- Losartan EP Impurity L (CAS 230971-71-8)
- Losartan EP Impurity M (CAS 230971-72-9)
- Losartan Impurity 33 (CAS CATO-C4X-168333)
- Losartan Potassium EP Impurity M (CAS 212316-88-6（free base）)
- Losartan Impurity 20 (CAS 1846587-44-7)
- Losartan Impurity 52 (CAS CATO-C4X-168352)
- Losartan impurity 32 (CAS CATO-C4X-168332)
- Losartan Impurity N3 (CAS 133910-00-6)
Recommended Standards
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Why CATO?
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