Gemcitabine Impurity 11 CAS 143157-25-9
| CAS No. | 143157-25-9 |
| Molecular Formula | C19H16F2O6 |
| Molecular Weight | 378.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 378.32 g/mol gives Gemcitabine Impurity 11 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Gemcitabine Impurity 11 (CAS 143157-25-9), a certified reference material (molecular formula C19H16F2O6, MW 378.32 g/mol) for analytical method development and quality control.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution, Gemcitabine Impurity 11 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 378.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Gemcitabine Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H16F2O6 |
| Molecular Weight | 378.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
Related Gemcitabine Standards
- Gemcitabine Impurity 16 (CAS 1173824-58-2)
- Gemcitabine Impurity 9 (CAS 143157-22-6)
- Gemcitabine Impurity 10 (CAS 1217452-91-9)
- Gemcitabine Impurity 17 (CAS 197452-15-6)
- Gemcitabine Impurity 29 (CAS 122111-02-8)
- Gemcitabine Impurity 32 (CAS 122111-01-7)
- Gemcitabine monophosphate (disodium) (CAS 1638288-31-9)
- Gemcitabine Impurity 31 (CAS 142816-70-4)
Recommended Standards
- (2R,3R)-4,4-Difluoro-2,5-dihydroxypentane-1,3-diyl dibenzoate (CAS 153012-08-9)
- methyl 2-{[di(pentyloxy)phosphoryl]oxy}-3,3,3-trifluoropropanoate (CAS 108682-54-8)
- 1-Phenyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]piperazine (CAS 2096339-39-6)
- threo-Mefloquine HCl (CAS 51744-85-5)
- 3-(4-Chloro-1H-pyrazol-1-yl)cyclohexan-1-one (CAS 1510319-14-8)
- Ethyl 2-(4-bromophenyl)-2-methylpropanoate (CAS 32454-36-7)
- 2-Bromo-4-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-1-(trifluoromethyl)benzene (CAS 1779132-37-4)
- 2-Bromo-4-(tert-pentyl)phenyl 4-piperidinyl etherhydrochloride (CAS 1220020-49-4)
- 6-Fluoro-3-propylquinolin-2-amine (CAS 948293-78-5)
- 1-((3-Ethyl-2-(4-nitrophenyl)imidazolidin-1-yl)methyl)-1H-benzo[d][1,2,3]triazole (CAS 433219-44-4)
- Butane-1,1-diyl dimethanesulfonate (CAS 81495-76-3)
- 5-Isopropyl-4-nitro-1H-pyrazole-3-carboxylic acid (CAS 141721-97-3)
- 2-(3-Methoxyphenyl)-7,8-dimethylquinoline-4-carbonyl chloride (CAS 1160261-30-2)
- Semaglutide impurity 72 (CAS CATO-C4X-222672)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com