Chlortalidone Impurity 4 CAS 118-04-7
| CAS No. | 118-04-7 |
| Molecular Formula | C14H10ClNO3 |
| Molecular Weight | 275.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 275.69 g/mol gives Chlortalidone Impurity 4 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Chlortalidone Impurity 4 (CAS 118-04-7), molecular formula C14H10ClNO3 and molecular weight 275.69 g/mol, is a CATO reference standard with documented purity and traceability.
Chlortalidone Impurity 4 (C14H10ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Chlortalidone Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H10ClNO3 |
| Molecular Weight | 275.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlortalidone Standards
- Chlortalidone Impurity 8 (CAS 2224-77-3)
- Chlortalidone EP Impurity B (CAS 5270-74-6)
- Chlortalidone EP Impurity A (CAS 345930-32-7)
- Chlortalidone Sulfochloro Impurity (CAS 68592-12-1)
- Chlortalidone EP Impurity D (CAS 1369995-36-7)
- Chlortalidone EP Impurity C (CAS 92874-73-2)
- Chlortalidone Impurity 6 (CAS 68592-11-0)
- Chlortalidone EP Impurity I (CAS 2514668-27-8)
Recommended Standards
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- 2-((4-Chlorobenzyl)amino)-1H-purin-6(9H)-one (CAS 123994-85-4)
- Amino(6-methyl(1,2,3,4-tetrahydroquinol-1-yl))methane-1-thione (CAS 1016755-37-5)
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- (R)-(1-((Benzyloxy)methyl)-2,2-difluorocyclopropyl)methanol (CAS 2852766-18-6)
- rel-2,5-Dioxopyrrolidin-1-yl (((2R,3R)-1-methyl-2-(pyridin-3-yl)pyrrolidin-3-yl)methyl) succinate (CAS 1207282-60-7)
- 2-Bromo-1-chloro-4-fluoro-3-methylbenzene (CAS 1806971-78-7)
- 1-(4-Bromo-5-fluoro-2-methylphenyl)ethanone (CAS 2091247-32-2)
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