Chlortalidone EP Impurity D CAS 1369995-36-7
| CAS No. | 1369995-36-7 |
| Molecular Formula | C16H15ClN2O4S |
| Molecular Weight | 366.82 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Chlortalidone EP Impurity D (CAS 1369995-36-7) is a certified pharmaceutical impurity reference standard with the molecular formula C16H15ClN2O4S and a molecular weight of 366.82 g/mol.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, Chlortalidone EP Impurity D is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 366.82 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Chlortalidone EP Impurity D under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H15ClN2O4S |
| Molecular Weight | 366.82 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlortalidone Standards
- Chlortalidone EP Impurity C (CAS 92874-73-2)
- Chlortalidone Sulfochloro Impurity (CAS 68592-12-1)
- Chlortalidone Impurity 6 (CAS 68592-11-0)
- Chlortalidone EP Impurity I (CAS 2514668-27-8)
- Chlortalidone EP Impurity A (CAS 345930-32-7)
- Chlortalidone EP Impurity B (CAS 5270-74-6)
- Chlortalidone Impurity 4 (CAS 118-04-7)
- Chlortalidone Impurity 8 (CAS 2224-77-3)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com