Chlortalidone EP Impurity I CAS 2514668-27-8
| CAS No. | 2514668-27-8 |
| Molecular Formula | C17H16ClNO5S |
| Molecular Weight | 381.83 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Chlortalidone EP Impurity I (C17H16ClNO5S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 381.83 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Chlortalidone EP Impurity I (CAS 2514668-27-8, C17H16ClNO5S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Chlortalidone EP Impurity I under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H16ClNO5S |
| Molecular Weight | 381.83 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chlortalidone Standards
- Chlortalidone Impurity 6 (CAS 68592-11-0)
- Chlortalidone EP Impurity C (CAS 92874-73-2)
- Chlortalidone EP Impurity D (CAS 1369995-36-7)
- Chlortalidone Sulfochloro Impurity (CAS 68592-12-1)
- Chlortalidone EP Impurity A (CAS 345930-32-7)
- Chlortalidone EP Impurity B (CAS 5270-74-6)
- Chlortalidone Impurity 4 (CAS 118-04-7)
- Chlortalidone Impurity 8 (CAS 2224-77-3)
Recommended Standards
- Indapamide Impurity 8 (CAS 126750-70-7)
- (E)-({6-chloro-2-phenylimidazo[1,2-a]pyridin-3-yl}methylidene)amino thiophene-2-carboxylate (CAS 478257-31-7)
- Indapamide Impurity 23 (CAS CATO-C4X-140023)
- (E)-6-phenylimidazo[2,1-b]thiazole-5-carbaldehyde O-(4-chlorobenzoyl) oxime (CAS 338404-80-1)
- Tamoxifen Impurity 27 (CAS CATO-C4X-123327)
- Dabrafenib Impurity 30 (CAS CATO-C4X-303330)
- Vericiguat Impurity 90 (CAS CATO-C4X-289690)
- N2-(4-Chlorophenyl)-5-(2,4-dichlorobenzoyl)-1,3-thiazole-2,4-diamine (CAS 339020-13-2)
- Ethyl 2-amino-4-(4-chloro-5-methyl-1h-pyrazol-1-yl)butanoate (CAS 1340081-61-9)
- tert-Butyl (2-chloroquinolin-4-yl)carbamate (CAS 1823510-39-9)
- 3-((2-Nitrobenzylidene)amino)quinazolin-4(3H)-one (CAS 88404-50-6)
- Ethyl({[4-(4-methoxypiperidin-1-yl)phenyl]methyl})amine (CAS 1096865-58-5)
- Eletriptan (CAS 143322-58-1)
- FMRF-Like Neuropeptide (CAS 121801-61-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com