Imatinib EP Impurity C CAS 404844-02-6
| CAS No. | 404844-02-6 |
| Molecular Formula | C28H29N7O |
| Molecular Weight | 479.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Imatinib EP Impurity C (CAS 404844-02-6) is a certified pharmaceutical impurity reference standard with the molecular formula C28H29N7O and a molecular weight of 479.58 g/mol.
The molecular framework of Imatinib EP Impurity C (C28H29N7O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Imatinib EP Impurity C meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H29N7O |
| Molecular Weight | 479.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 7 |
Related Imatinib Standards
- Imatinib EP Impurity C-d8 (N-Desmethyl Imatinib-d8) (CAS 1185103-28-9)
- Imatinib Impurity 10 (CAS 1026753-54-7)
- Imatinib (CAS 152459-95-5)
- Imatinib meta-MPM Impurity (CAS 1246819-59-9)
- Imatinib Impurity 65 (CAS CATO-C4X-106865)
- Imatinib Impurity 73 (CAS CATO-C4X-106873)
- Imatinib-d3 (N-methyl-d3) (CAS 1134803-18-1)
- Imatinib-d3 (CAS 1144803-18-1)
Recommended Standards
- Ensifentrine impurity 31 (CAS CATO-C4X-335331)
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- 4-chlorophenylethanol (CAS 1875-88-3)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com