Enzalutamide Impurity 20 CAS 1187368-67-7
| CAS No. | 1187368-67-7 |
| Molecular Formula | C9H11FN2O |
| Molecular Weight | 182.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 182.19 g/mol gives Enzalutamide Impurity 20 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Enzalutamide Impurity 20 (CAS 1187368-67-7) is a certified pharmaceutical impurity reference standard with the molecular formula C9H11FN2O and a molecular weight of 182.19 g/mol.
Structurally, Enzalutamide Impurity 20 (C9H11FN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 182.19 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Enzalutamide Impurity 20 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H11FN2O |
| Molecular Weight | 182.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Enzalutamide Standards
- Enzalutamide Impurity 24 (CAS 403-24-7)
- Enzalutamide Impurity 19 (CAS 73792-08-2)
- Enzalutamide Impurity N4 (CAS 869936-86-7)
- Enzalutamide Impurity 22 (CAS 392-09-6)
- Enzalutamide Impurity 36 (CAS 208122-06-9)
- Enzalutamide Impurity 33 (CAS 934600-95-0)
- Enzalutamide Impurity 21 (CAS 446-31-1)
- Enzalutamide Impurity 35 (CAS 888072-96-6)
Recommended Standards
- 905587-17-9 N-[(1S)-1-(5-Fluoropyridin-2-yl)ethyl]acetamide DTXSID70735670 (CAS 905587-17-9)
- Haloperidol Impurity 23 (CAS 73206-04-9)
- 866023-55-4 N-(3-Amino-4-fluorophenyl)propanamide DTXSID70588289 (CAS 866023-55-4)
- Hydantoin Impurity 4 (CAS 2361-15-1)
- Donepezil Impurity 56 HCI (CAS 608511-44-0（free base）)
- Lenvatinib Impurity 64 (CAS 2174956-62-6)
- Ulipristal Impurity 19 (CAS CATO-C4X-191519)
- 7-Chloro-5-ethyl-3-methylisoxazolo[4,5-d]pyrimidine (CAS 1268519-94-3)
- (S)-1-(4-Aminophenyl)ethan-1-ol (CAS 500229-84-5)
- Orforglipron Impurity 108 (CAS CATO-C4X-3234108)
- (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-methoxyphenyl)propanoic acid (CAS 206060-41-5)
- 2'-((2-Methoxy-9H-fluoren-3-yl)carbamoyl)-[1,1'-biphenyl]-2-carboxylic acid (CAS 27021-97-2)
- N1-Desmethyl EDC (CAS 35271-22-8)
- Cholecystokinin, CCK Tetrapeptide (30-33) (CAS 35144-91-3)
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