Enzalutamide Impurity 21 CAS 446-31-1
| CAS No. | 446-31-1 |
| Molecular Formula | C7H6FNO2 |
| Molecular Weight | 155.13 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 155.13 g/mol gives Enzalutamide Impurity 21 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Enzalutamide Impurity 21 (CAS 446-31-1), a pharmacopoeial impurity reference standard (molecular formula C7H6FNO2, MW 155.13 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, Enzalutamide Impurity 21 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 155.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Enzalutamide Impurity 21 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H6FNO2 |
| Molecular Weight | 155.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Enzalutamide Standards
- Enzalutamide Impurity N4 (CAS 869936-86-7)
- Enzalutamide Impurity 19 (CAS 73792-08-2)
- Enzalutamide Impurity 20 (CAS 1187368-67-7)
- Enzalutamide Impurity 24 (CAS 403-24-7)
- Enzalutamide Impurity 22 (CAS 392-09-6)
- Enzalutamide Impurity 36 (CAS 208122-06-9)
- Enzalutamide Impurity 33 (CAS 934600-95-0)
- Enzalutamide Impurity 35 (CAS 888072-96-6)
Recommended Standards
- 4-Fluoroanthranilic Acid (CAS 446-32-2)
- Osimertinib Impurity 111 (CAS 450-84-0)
- 4-fluoro-6-[(hydroxyamino)methylidene]cyclohexa-2,4-dien-1-one 91407-40-8 (CAS 91407-40-8)
- 2-Nitrobenzaldehyde-d (CAS 1020718-69-7)
- Nicorandil Impurity 41 (CAS CATO-C4X-190741)
- Perindopril Impurity 69 (CAS 145513-92-4 (free base))
- Desmopressin Impurity 47 (CAS CATO-C4X-221547)
- m-Toluic Acid (CAS 99-04-7)
- 1-(tert-Butyldimethylsilyl)indole-5-carbaldehyde (CAS 946077-36-7)
- 1,19-Difluorononadecan-10-One (CAS 462-17-9)
- tert-butyl N-(6-bromothiazolo[4,5-b]pyrazin-2-yl)carbamate (CAS 2680840-90-6)
- 4-(4-{[1,4'-bipiperidine]-1'-yl}-3-nitrophenyl)-1,2-dihydrophthalazin-1-one (CAS 882000-45-5)
- 2-Pyrrolidinomethyl-2-trifluoromethylbenzophenone (CAS 898774-79-3)
- Semaglutide impurity 41 (CAS CATO-C4X-222641)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com