Iloperidone Impurity 8 CAS 1209459-88-0
| CAS No. | 1209459-88-0 |
| Molecular Formula | C7H7BrN2O |
| Molecular Weight | 215.05 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Iloperidone Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Iloperidone Impurity 8 (CAS 1209459-88-0) is a certified pharmaceutical impurity reference standard with the molecular formula C7H7BrN2O and a molecular weight of 215.05 g/mol.
The molecular framework of Iloperidone Impurity 8 (C7H7BrN2O) is characterized by an amide group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C7H7BrN2O |
| Molecular Weight | 215.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Iloperidone Standards
- Iloperidone Impurity 19 (CAS 54771-60-7)
- Iloperidone Impurity 3 (CAS 792857-93-3)
- Iloperidone Impurity 31 (CAS 116218-80-5)
- Iloperidone Impurity 1 (CAS 207298-39-3)
- Iloperidone Impurity 11 (CAS 59084-16-1)
- Iloperidone Stage -I Impurity (CAS 58113-30-7)
- Iloperidone Impurity 6 (CAS 3245-49-6)
- Iloperidone Impurity 15 (CAS 81055-36-9)
Recommended Standards
- Vortioxetine Impurity 100 (CAS 17576-86-2)
- Isavuconazole Impurity N16 (CAS 2491-38-5)
- N-(6-Bromopyridin-3-yl)acetamide (CAS 29958-19-8)
- 1-bromo-6-fluoro-2,3-dihydro-1H-indene (CAS 1188147-00-3)
- Semaglutide impurity 93 (CAS CATO-C4X-222693)
- Sacubitril Impurity 34 (CAS CATO-C4X-280934)
- Levothyroxine EP Impurity C (CAS 51-24-1)
- 2-{1H-pyrrolo[3,2-h]quinolin-2-yl}pyridine (CAS 397299-84-2)
- Rel-methyl (1R,2R)-2-methylcyclopropane-1-carboxylate (CAS 56695-88-6)
- 2-[(4-{[(tert-butoxy)carbonyl]amino}butyl)sulfanyl]acetic acid (CAS 1555902-59-4)
- 4-Bromo-1-(3,5-difluorophenyl)-1H-imidazole (CAS 1353855-80-7)
- (S)-3-Amino-2-(4-methoxy-phenyl)-propionic acid 293731-68-7 KS-000025MB (CAS 293731-68-7)
- 2-(Difluoromethoxy)naphthalene-5-methanol (CAS 1261844-33-0)
- Autocamtide-2-Related Inhibitory Peptide TFA (CAS 167114-91-2（free base）)
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