Tenofovir alafenamide Impurity 14 CAS 1234081-04-9
| CAS No. | 1234081-04-9 |
| Molecular Formula | C18H23N6O5P |
| Molecular Weight | 434.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Tenofovir alafenamide Impurity 14 (CAS 1234081-04-9, C18H23N6O5P) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, Tenofovir alafenamide Impurity 14 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 434.39 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Tenofovir alafenamide Impurity 14 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H23N6O5P |
| Molecular Weight | 434.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 6 |
Related Tenofovir Standards
- Tenofovir disoproxil Impurity 21 (CAS 1244022-55-6)
- Tenofovir disoproxil Impurity 100 (CAS 1796539-92-8)
- Tenofovir disoproxil Impurity 54 (CAS 1878175-76-8)
- Tenofovir disoproxil Impurity 137 (CAS CATO-C4X-1076137)
- Tenofovir Alafenamide Impurity 1 (CAS 342631-41-8)
- Tenofovir Diphosphate (CAS 166403-66-3)
- Tenofovir disoproxil Impurity 113 (CAS CATO-C4X-1076113)
- Tenofovir alafenamide Impurity 16 Free base (CAS CATO-C4X-179769)
Recommended Standards
- 2-(difluoro(3,4,5-trifluorophenoxy)methyl)-1,3-difluoro-5-((1s,4r)-4-propylcyclohexyl)benzene (CAS 208338-62-9)
- Difamilast Impurity 5 (CAS 2103190-81-2)
- Isosalipurposide - API Standards (CAS 4547-85-7)
- Difamilast Impurity 8 (CAS 2103190-85-6)
- Tenofovir disoproxil Impurity 49 (CAS 1244022-56-7)
- Ceritinib Impurity 16 (CAS CATO-C4X-104816)
- Methocarbamol Impurity 8 (CAS CATO-C4X-24448)
- 3-(3-Chloro-4-hydroxyphenyl)-3-hydroxypropanoic acid (CAS 1248246-33-4)
- 6-Methylbenzo[d][1,2,3]triazin-4(1H)-one (CAS 91532-23-9)
- 4-(6-Iodopyrazin-2-yl)morpholine (CAS 1242241-01-5)
- 3,4-Dicyanobenzoic acid (CAS 60469-86-5)
- 1-amino-3-isobutoxypropan-2-ol (CAS 60755-67-1)
- [2-(4-Fluorophenyl)cyclopropyl]amine HCl (CAS 879324-66-0)
- Tirzepatide Impurity 52 (CAS CATO-C4X-324052)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com