Tenofovir alafenamide Impurity 16 Free base CAS CATO-C4X-179769

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-179769
Molecular FormulaC19H25N6O5P
Molecular Weight448.41 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Tenofovir alafenamide Impurity 16 Free base CAS CATO-C4X-179769 chemical structure

Description

Tenofovir alafenamide Impurity 16 Free base (CAS CATO-C4X-179769) is a certified pharmaceutical impurity reference standard with the molecular formula C19H25N6O5P and a molecular weight of 448.41 g/mol.

The molecular framework of Tenofovir alafenamide Impurity 16 Free base (C19H25N6O5P) is characterized by a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Tenofovir alafenamide Impurity 16 Free base under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC19H25N6O5P
Molecular Weight448.41 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)10.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms6

Related Tenofovir Standards

Recommended Standards

Why CATO?