Haloperidol impurity 40 CAS 1253910-15-4
| CAS No. | 1253910-15-4 |
| Molecular Formula | C14H18FNO2 |
| Molecular Weight | 251.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Haloperidol impurity 40 (CAS 1253910-15-4), a pharmacopoeial impurity reference standard (molecular formula C14H18FNO2, MW 251.30 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Haloperidol impurity 40 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 251.30 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Haloperidol impurity 40 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H18FNO2 |
| Molecular Weight | 251.30 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Haloperidol Standards
- Haloperidol Impurity N16 (CAS 57390-39-3)
- Haloperidol Impurity 17 (CAS 63843-83-4)
- Haloperidol Impurity 13 (CAS 17135-46-5)
- Haloperidol impurity 02 (CAS 121751-79-9)
- Haloperidol Impurity 19 (CAS 71501-46-7)
- Haloperidol Impurity 18 (CAS 2823-19-0)
- Haloperidol Impurity 21 (CAS 3874-54-2)
- Haloperidol impurity 24 (CAS 3110-52-9)
Recommended Standards
- Fasudil Impurity 34 (CAS CATO-C4X-136534)
- Linezolid Impurity 19 (CAS CATO-C4X-153519)
- Fasudil Impurity 33 (CAS CATO-C4X-136533)
- Rasagiline Impurity 5 (CAS CATO-C4X-19135)
- Bilastine Impurity 54 (CAS CATO-C4X-225354)
- Alfacalcidol EP Impurity C (CAS 82266-85-1)
- Venetoclax Impurity 135 (CAS CATO-C4X-2495135)
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- 4-(3-Isopropyl-1,2,4-oxadiazol-5-yl)phenol (CAS 1189749-24-3)
- N,2-Dimethyl-N-[(phenylmethyl)sulfonyl]-alanine (CAS 1284294-94-5)
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- 8-Methoxy-4-oxo-2-(trifluoromethyl)-4H-pyrido[1,2-a]pyrimidine-3-carbonitrile (CAS 2648788-55-8)
- Characteristic MSH-Tetrapeptide (CAS 4289-02-5)
Why CATO?
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com