Haloperidol Impurity 18 CAS 2823-19-0
| CAS No. | 2823-19-0 |
| Molecular Formula | C10H10ClFO |
| Molecular Weight | 200.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Haloperidol Impurity 18.
As a process- or degradation-related impurity, Haloperidol Impurity 18 (CAS 2823-19-0, C10H10ClFO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Haloperidol Impurity 18 (C10H10ClFO) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Haloperidol Impurity 18 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H10ClFO |
| Molecular Weight | 200.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
Related Haloperidol Standards
- Haloperidol Impurity 21 (CAS 3874-54-2)
- Haloperidol impurity 24 (CAS 3110-52-9)
- Haloperidol impurity 02 (CAS 121751-79-9)
- Haloperidol Impurity 19 (CAS 71501-46-7)
- Haloperidol Impurity 13 (CAS 17135-46-5)
- Haloperidol Impurity N1 (CAS 939-52-6)
- Haloperidol Impurity 23 (CAS 73206-04-9)
- Haloperidol Impurity 37 (CAS 84819-46-5)
Recommended Standards
- propan-2-yl 2-(chlorosulfonyl)acetate (CAS 303153-12-0)
- Methyl 4-chlorosulfonyl-butanoate (CAS 81926-28-5)
- Methyl 3-(chlorosulfonyl)-2-methylpropanoate (CAS 927966-06-1)
- 3-Chloro-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine (CAS 100859-88-9)
- Betahistine impurity 31 (CAS 91029-17-3)
- Estetrol Impurity 5 (CAS CATO-C4X-32505)
- Esomeprazole Impurity 101 (CAS 84006-10-0)
- 1-[(2,5-dimethylphenyl)methyl]-2-methyl-1h-indole-3-carbaldehyde (CAS 174727-79-8)
- 4-(Aminomethyl)-N-cyclopropylpyridin-2-amine (CAS 1247702-69-7)
- Phenyl(3-phenylquinoxalin-2-yl)methanone (CAS 5784-78-1)
- [(4-Methylquinolin-2-yl)sulfanyl]acetic acid (CAS 17880-62-5)
- Amifampridine Phosphate (CAS 446254-47-3)
- Zolpidem Impurity N16 (CAS 768398-03-4)
- (Met(O)2?)-Glucagon (1-29) (human, rat, porcine) (CAS 75217-63-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com