Alectinib Impurity 48 CAS CATO-C4X-283648
| CAS No. | CATO-C4X-283648 |
| Molecular Formula | C20H20N2 |
| Molecular Weight | 288.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 288.39 g/mol gives Alectinib Impurity 48 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Alectinib Impurity 48 (CAS CATO-C4X-283648, C20H20N2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Alectinib Impurity 48 (C20H20N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Alectinib Impurity 48 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H20N2 |
| Molecular Weight | 288.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Alectinib Standards
- Alectinib Impurity 58 (CAS CATO-C4X-283658)
- Alectinib Impurity 1 (CAS 1256578-99-0)
- Alectinib impurity 01 (CAS 1256584-82-3)
- Alectinib Impurity 69 (CAS CATO-C4X-283669)
- Alectinib Impurity 67 (CAS CATO-C4X-283667)
- Alectinib Impurity 3 (CAS 1256584-73-2)
- Alectinib Impurity 91 (CAS CATO-C4X-283691)
- Alectinib impurity 27 (CAS CATO-C4X-283627)
Recommended Standards
- Demiditraz Impurity 2 (CAS 944268-65-9)
- Alpha-Hydroxy Metoprolol-d5 (Mixture of Diastereomers) (CAS 1189934-03-9)
- Pentoxyverine Impurity 10 (CAS CATO-C4X-227010)
- N,N''-Bis(methylphenyl)-1,4-benzenediamine (CAS 27417-40-9)
- Vinpocetine Impurity 18 (CAS 18374-18-0)
- Maxacalcitol Impurity 24 (CAS CATO-C4X-278824)
- Sulfamethoxazole EP Impurity A (CAS 21312-10-7)
- 4-amino-2,3,3-trimethylbutan-2-ol (CAS 1540802-12-7)
- 3-(4-methoxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazine-6-thiol (CAS 901273-03-8)
- (4-(4-Chloro-1h-pyrazol-1-yl)phenyl)methanamine (CAS 1006442-29-0)
- (3-Bromo-5-chloro-2-methylphenyl)boronic acid (CAS 2225155-54-2)
- 5beta-Dutasteride (CAS 957229-52-6)
- 5-BROMO-3-(1-METHYL-1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-INDOLE (CAS 116480-53-6)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com