Alectinib Impurity 12 CAS 1256584-77-6
| CAS No. | 1256584-77-6 |
| Molecular Formula | C34H44N4O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Alectinib Impurity 12 (CAS 1256584-77-6), a pharmacopoeial impurity reference standard (molecular formula C34H44N4O3HCl, MW 593.21 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Alectinib Impurity 12 (C34H44N4O3HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 593.21 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Alectinib Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C34H44N4O3 HCl |
| Molecular Weight | 593.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Alectinib Standards
- Alectinib Impurity 5 (CAS 1247119-83-0)
- Alectinib Impurity 1 (CAS 1256578-99-0)
- Alectinib Impurity 2 (CAS 1256579-06-2)
- Alectinib (CAS 1256580-46-7)
- Alectinib Impurity 4 (CAS 1256584-72-1)
- Alectinib Impurity 3 (CAS 1256584-73-2)
- Alectinib Impurity 10 (CAS 1256584-74-3)
- Alectinib Impurity 14 (CAS 1256584-78-7)
Recommended Standards
- Neostigmine impurity 39 (CAS CATO-C4X-204239)
- Clindamycin Impurity 130 (CAS CATO-C4X-1341130)
- Atrasentan Impurity 154 (CAS 1058404-07-1)
- 2-(Benzylamino)pyrimidine-5-carbaldehyde (CAS 946778-44-5)
- 2-Thiabicyclo[3.1.0]hex-3-ene-6-carboxylic acid (CAS 856656-74-1)
- 1-(Furan-3-ylmethyl)-1-(2-methoxyethyl)-3-(o-tolyl)urea (CAS 1421451-55-9)
- Methyl 2,4-dichloroquinoline-7-carboxylate (CAS 2095162-11-9)
- Aciclovir EP Impurity L (CAS 3056-33-5)
- 2-(8-Methoxy-6-methyl-4-oxoquinolin-1(4H)-yl)acetonitrile (CAS 1315345-06-2)
- Des-Tyr10-Tirzepatide (CAS CATO-CPTD788680)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com