Tenofovir alafenamide impurity 79 CAS 126771-33-3
| CAS No. | 126771-33-3 |
| Molecular Formula | C13H17NO3 |
| Molecular Weight | 235.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Tenofovir alafenamide impurity 79 (CAS 126771-33-3) is a certified pharmaceutical impurity reference standard with the molecular formula C13H17NO3 and a molecular weight of 235.28 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Tenofovir alafenamide impurity 79 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 235.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), Tenofovir alafenamide impurity 79 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H17NO3 |
| Molecular Weight | 235.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 1 |
Related Tenofovir Standards
- Tenofovir alafenamide impurity 80 (CAS 126771-36-6)
- Tenofovir alafenamide impurity 82 (CAS 126771-32-2)
- Tenofovir alafenamide Impurity 79 (CAS 102-10-3)
- Tenofovir Impurity 59 (CAS 116384-56-6)
- Tenofovir alafenamide impurity 85 (CAS 121149-98-2)
- Tenofovir disoproxil Impurity 42 (CAS 1878175-82-6)
- Tenofovir Alafenamide Impurity 26 (CAS CATO-C4X-179726)
- Tenofovir Alafenamide Impurity 47 (CAS 1884329-63-8)
Recommended Standards
- Lidocaine Impurity 69 (CAS CATO-C4X-167969)
- Lidocaine impurity 65 (CAS CATO-C4X-167965)
- Parecoxib Impurity 45 (CAS 75115-00-3)
- Etomidate Impurity 20 (CAS CATO-C4X-188420)
- Calcium Dobesilate impurity 18 (CAS CATO-C4X-205118)
- Candesartan Cilexetil Impurity 35 (CAS 1867269-67-7)
- Edaravone Impurity 1 (CAS 1357477-99-6)
- Potassium 4-nitrobenzoate (CAS 15922-01-7)
- 3-Oxo-4-(4-chlorophenyl)butanoyl chloride (CAS 1987320-77-3)
- Tert-butyl (3-oxo-2-azaspiro[4.5]Decan-8-yl)carbamate (CAS 2306272-78-4)
- Otilonium Bromide Impurity 8 (CAS 5455-95-8)
- Ivabradine impurity 79 (CAS 2768438-46-4)
- 2-(Thiophen-3-yl)cycloheptan-1-ol (CAS 1478805-17-2)
- Copper Peptide ·2 acetate salt (CAS 130120-57-9)
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