Tenofovir disoproxil Impurity 42 CAS 1878175-82-6
| CAS No. | 1878175-82-6 |
| Molecular Formula | C11H17N5O2 |
| Molecular Weight | 251.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Tenofovir disoproxil Impurity 42 is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Tenofovir disoproxil Impurity 42 (CAS 1878175-82-6, C11H17N5O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Tenofovir disoproxil Impurity 42 (C11H17N5O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Tenofovir disoproxil Impurity 42 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H17N5O2 |
| Molecular Weight | 251.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 5 |
Related Tenofovir Standards
- Tenofovir Alafenamide Impurity 26 (CAS CATO-C4X-179726)
- Tenofovir Alafenamide Impurity 47 (CAS 1884329-63-8)
- Tenofovir disoproxil Impurity 3 (CAS 52364-31-5)
- Tenofovir Impurity 38 (CAS 161760-09-4)
- Tenofovir alafenamide impurity 79 (CAS 126771-33-3)
- Tenofovir alafenamide impurity 80 (CAS 126771-36-6)
- Tenofovir alafenamide impurity 82 (CAS 126771-32-2)
- Tenofovir alafenamide Impurity 79 (CAS 102-10-3)
Recommended Standards
- N-(tert-Butoxycarbonyl)-D-2-phenylglycine (CAS 33125-05-2)
- rac-Amoxicillin EP Impurity H (CAS 106644-43-3)
- N-(tert-Butoxycarbonyl)-L-2-phenylglycine (CAS 2900-27-8)
- Amoxicillin EP Impurity H (CAS 205826-86-4)
- Atazanavir EP Impurity G (CAS 1332981-16-4)
- Allopurinol impurity 20 (CAS CATO-C4X-145820)
- Tofacitinib Impurity 119 (CAS 2407039-29-4)
- 2-Amino-1-(2,5-difluorophenyl)propan-1-one (CAS 1216210-66-0)
- 2-[2-methyl-5-(propan-2-yl)phenoxy]acetic acid (CAS 19728-20-2)
- N-(2,6-dichlorophenyl)-N-chloroacetylamine (CAS 99310-46-0)
- 5-(5-Chloro-2-methoxybenzenesulfonyl)-3-(trifluoromethyl)-5H,6H,6aH,7H,8H,9H,10H-pyrido[1,2-a]quinoxaline (CAS 866041-05-6)
- 6-(Piperidine-1-carbonyl)-5,6,7,8-tetrahydrocinnolin-3(2H)-one (CAS 1707567-59-6)
- Baclofen Impurity 28 (CAS 70410-34-3)
- (Tyr9)-Cholecystokinin Octapeptide (sulfated) (H-9770.0005) (CAS 96607-61-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com