Paroxetine Hemihydrate EP Impurity B HCl CAS 127017-74-7
| CAS No. | 127017-74-7 |
| Molecular Formula | C20H23NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Paroxetine Hemihydrate EP Impurity B HCl.
Paroxetine Hemihydrate EP Impurity B HCl (CAS 127017-74-7) is a certified pharmaceutical impurity reference standard with the molecular formula C20H23NO4HCl and a molecular weight of 377.86 g/mol.
Based on its molecular formula C20H23NO4HCl, Paroxetine Hemihydrate EP Impurity B HCl contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 377.86 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Paroxetine Hemihydrate EP Impurity B HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H23NO4 HCl |
| Molecular Weight | 377.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Paroxetine Standards
- Paroxetine Impurity 62 (CAS 100332-12-5)
- Paroxetine Impurity 43 (CAS 100332-20-5)
- Paroxetine EP Impurity G HCl (CAS 1012886-75-7)
- Paroxetine Impurity 24 (CAS 105812-81-5)
- Paroxetine EP impurity C (CAS 105813-14-7)
- Paroxetine HCl EP Impurity C (CAS 105813-14-7(free base))
- Paroxetine EP Impurity F HCl (CAS 105813-39-6)
- Paroxetine Impurity 47 (CAS 105813-40-9)
Recommended Standards
- Tenofovir Impurity 64 (CAS CATO-C4X-107664)
- Verapamil Hydrochloride EP Impurity E (CAS 93-03-8)
- Venlafaxine Impurity 77 (CAS CATO-C4X-143477)
- 5-(5-Cyclopropylisoxazol-3-yl)-1,3,4-oxadiazol-2-amine (CAS 1248908-01-1)
- tert-Butyl 7-cyano-3,4-dihydro-2,6-naphthyridine-2(1H)-carboxylate (CAS 2750527-52-5)
- 2-chloro-5-methoxybenzenesulfonamide (CAS 502187-53-3)
- 2-(2-(Trifluoromethyl)phenyl)acetimidamide (CAS 903094-74-6)
- N-(2-Cyano-4,5-dimethoxyphenyl)-N-[3-(trifluoromethyl)benzyl]thiourea (CAS 477858-82-5)
- (S)-2-(Fmoc-amino)-4,4,4-trifluorobutanoic Acid (CAS 181128-48-3)
- Myosin Kinase Inhibiting Peptide (CAS 119386-39-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com