Rimegepant Impurity 19 CAS 1289024-04-9

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.1289024-04-9
Molecular FormulaC25H34ClF2NOSi
Molecular Weight466.08 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Rimegepant Impurity 19 CAS 1289024-04-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 466.08 g/mol gives Rimegepant Impurity 19 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Rimegepant Impurity 19 (CAS 1289024-04-9) is a certified pharmaceutical impurity reference standard with the molecular formula C25H34ClF2NOSi and a molecular weight of 466.08 g/mol.

Structurally, Rimegepant Impurity 19 (C25H34ClF2NOSi) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 466.08 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Rimegepant Impurity 19 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC25H34ClF2NOSi
Molecular Weight466.08 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity>95%
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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