Avatrombopag Impurity 5 CAS 1290121-42-4
| CAS No. | 1290121-42-4 |
| Molecular Formula | C29H35ClN6O4S2 |
| Molecular Weight | 631.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C29H35ClN6O4S2, Avatrombopag Impurity 5 contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 631.21 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a process- or degradation-related impurity, Avatrombopag Impurity 5 (CAS 1290121-42-4, C29H35ClN6O4S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Avatrombopag Impurity 5 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C29H35ClN6O4S2 |
| Molecular Weight | 631.21 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 2 |
Related Avatrombopag Standards
- Avatrombopag Impurity 22 (CAS CATO-C4X-223422)
- Avatrombopag Impurity 100 (CAS CATO-C4X-2234100)
- Avatrombopag Impurity 142 (CAS CATO-C4X-2234142)
- Avatrombopag Impurity 137 (CAS CATO-C4X-2234137)
- Avatrombopag Impurity 57 (CAS CATO-C4X-223457)
- Avatrombopag Impurity 121 (CAS CATO-C4X-2234121)
- Avatrombopag impurity 136 (CAS CATO-C4X-2234136)
- Avatrombopag (CAS 570406-98-3)
Recommended Standards
- Solaneso (CAS 13190-97-1)
- Carbonylchlorohydrido[bis(2-di-cyclohexylphosphinoethyl)amine]ruthenium(II) (CAS 1421060-11-8)
- Relugolix Impurity 101 (CAS CATO-C4X-2429101)
- N-(3-(5-Bromo-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide (CAS 1262985-24-9)
- Donepezil EP impurity B (CAS 2107-69-9)
- Nimodipine Impurity 11 (CAS CATO-C4X-138511)
- Azilsartan Impurity 135 (CAS 209551-67-7)
- 4-[(phenylamino)methyl]aniline (CAS 24007-66-7)
- Promethazine EP Impurity D (CAS 7640-51-9)
- N-methoxy-N-methyl-2-(methylthio)nicotinamide (CAS 1208875-80-2)
- METHYL 3-(CHLOROSULFONYL)-4-ETHOXYBENZOATE (CAS 932896-53-2)
- N-Methyl-1,2,4-thiadiazol-5-amine (CAS 100703-97-7)
- Methyl 4-amino-2,2'-bithiophene-5-carboxylate (CAS 169759-79-9)
- Semaglutide impurity 259 (CAS CATO-C4X-2226259)
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