Avatrombopag Impurity 137 CAS CATO-C4X-2234137

Description

The occurrence of Avatrombopag Impurity 137 is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Avatrombopag Impurity 137 (CAS CATO-C4X-2234137), a pharmacopoeial impurity reference standard (molecular formula C29H35ClN6O3S2, MW 615.21 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C29H35ClN6O3S2, Avatrombopag Impurity 137 contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 615.21 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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