Demeclocycline EP Impurity C CAS 129044-45-7
| CAS No. | 129044-45-7 |
| Molecular Formula | C21H22N2O8 |
| Molecular Weight | 430.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Demeclocycline EP Impurity C (CAS 129044-45-7), a pharmacopoeial impurity reference standard (molecular formula C21H22N2O8, MW 430.41 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Demeclocycline EP Impurity C is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 430.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H22N2O8 |
| Molecular Weight | 430.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 2 |
Related Demeclocycline Standards
- Demeclocycline EP Impurity A (CAS 987-02-0)
- Demeclocycline impurity 12 (CAS CATO-C4X-160812)
- Demeclocycline EP Impurity F (CAS CATO-C4X-16086)
- Demeclocycline EP Impurity G (CAS 22688-73-9)
- Demeclocycline Impurity 10 (CAS CATO-C4X-160810)
- Demeclocycline EP Impurity E (CAS 4496-85-9)
- Demeclocycline Hydrochloride EP Impurity D (CAS 81181-91-1)
- Demeclocycline EP Impurity B (CAS 14206-59-8)
Recommended Standards
- Ketorolac impurity 61 (CAS CATO-C4X-166961)
- Rivaroxaban Impurity 165 (CAS CATO-C4X-1090165)
- Minocycline Impurity 68 (CAS CATO-C4X-169968)
- Pomalidomide-PEG2-C2-azide (CAS 2271036-45-2)
- Sertraline Impurity 75 (CAS CATO-C4X-134475)
- Cisatracurium Besilate EP Impurity T (CAS 112242-41-8)
- Olmesartan Impurity 43 (CAS 1227664-85-8)
- 2-(2-(Pyridin-3-yl)ethyl)benzoic acid hydrochloride (CAS 1185303-88-1)
- 3-fluoro-6-hydroxypyridine-2-carboxylic acid (CAS 604774-05-2)
- 2,3,4,6-Tetrafluorobenzeneboronic acid (CAS 511295-00-4)
- Ac-Gly-Ala-Val-Ile-Leu-Arg-Arg-NH2 trifluoroacetate salt (CAS 1092658-86-0)
- 2-(Decyloxy)ethan-1-ol (CAS 26183-52-8)
- trimethyl-[(Z)-1-propan-2-yloxybut-1-enoxy]silane (CAS 112274-95-0)
- Semaglutide impurity 36 (CAS CATO-C4X-222636)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com