Demeclocycline EP Impurity F CAS CATO-C4X-16086
| CAS No. | CATO-C4X-16086 |
| Molecular Formula | C21H19ClN2O7 |
| Molecular Weight | 446.84 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 446.84 g/mol gives Demeclocycline EP Impurity F distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Demeclocycline EP Impurity F (CAS CATO-C4X-16086) is a certified pharmaceutical impurity reference standard with the molecular formula C21H19ClN2O7 and a molecular weight of 446.84 g/mol.
Demeclocycline EP Impurity F (C21H19ClN2O7) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Demeclocycline EP Impurity F under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H19ClN2O7 |
| Molecular Weight | 446.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >85% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Demeclocycline Standards
- Demeclocycline EP Impurity G (CAS 22688-73-9)
- Demeclocycline EP Impurity A (CAS 987-02-0)
- Demeclocycline EP Impurity C (CAS 129044-45-7)
- Demeclocycline EP Impurity B (CAS 14206-59-8)
- Demeclocycline (CAS 127-33-3)
- Demeclocycline impurity 12 (CAS CATO-C4X-160812)
- Demeclocycline Impurity 10 (CAS CATO-C4X-160810)
- Demeclocycline EP Impurity E (CAS 4496-85-9)
Recommended Standards
- Amlodipine Impurity 17 (CAS CATO-C4X-109517)
- 3,3'-((2-Chlorophenyl)methylene)bis(4-hydroxy-2h-chromen-2-one) (CAS 4322-58-1)
- Resmetirom Impurity 32 (CAS CATO-C4X-291232)
- 2-(3-Nitrophenyl)-2-oxoethyl 6-chloro-2-phenylquinoline-4-carboxylate (CAS 355420-42-7)
- Trelagliptin Impurity 35 1/4Succinate (CAS CATO-C4X-104635)
- Gefitinib Impurity 33 (CAS 909863-33-8)
- Upadacitinib Impurity 16 (CAS 1428243-26-8)
- Fusidate Sodium (CAS 751-94-0)
- PAR-2 (1-6) (mouse, rat) (CAS 164081-25-8)
- 3-methyl-2-phenylbutanal (CAS 2439-44-3)
- 5-Chloro-N-(3-isopropoxybenzyl)-2-methylaniline (CAS 1040685-43-5)
- (Z)-2-Methylbut-2-enal (CAS 6038-09-1)
- 4-Chloro-2-(imidazolin-2-yl)Isoindoline hydrochloride (CAS 170034-96-5)
- Insulin Glulisine (CAS 207748-29-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com