Demeclocycline EP Impurity G CAS 22688-73-9
| CAS No. | 22688-73-9 |
| Molecular Formula | C21H19ClN2O7 |
| Molecular Weight | 446.84 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Demeclocycline EP Impurity G (CAS 22688-73-9) is a certified pharmaceutical impurity reference standard with the molecular formula C21H19ClN2O7 and a molecular weight of 446.84 g/mol.
The molecular framework of Demeclocycline EP Impurity G (C21H19ClN2O7) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Demeclocycline EP Impurity G under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H19ClN2O7 |
| Molecular Weight | 446.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Demeclocycline Standards
- Demeclocycline EP Impurity F (CAS CATO-C4X-16086)
- Demeclocycline EP Impurity A (CAS 987-02-0)
- Demeclocycline EP Impurity C (CAS 129044-45-7)
- Demeclocycline EP Impurity B (CAS 14206-59-8)
- Demeclocycline (CAS 127-33-3)
- Demeclocycline impurity 12 (CAS CATO-C4X-160812)
- Demeclocycline Impurity 10 (CAS CATO-C4X-160810)
- Demeclocycline EP Impurity E (CAS 4496-85-9)
Recommended Standards
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- 5-(Piperidin-4-yl)-1H-indole hydrochloride (CAS 1864074-77-0)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com