Demeclocycline EP Impurity E CAS 4496-85-9
| CAS No. | 4496-85-9 |
| Molecular Formula | C21H20N2O7 |
| Molecular Weight | 412.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 412.39 g/mol gives Demeclocycline EP Impurity E distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Demeclocycline EP Impurity E (CAS 4496-85-9) is a certified pharmaceutical impurity reference standard with the molecular formula C21H20N2O7 and a molecular weight of 412.39 g/mol.
Based on its molecular formula C21H20N2O7, Demeclocycline EP Impurity E contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 412.39 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Demeclocycline EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H20N2O7 |
| Molecular Weight | 412.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
Related Demeclocycline Standards
- Demeclocycline Impurity 10 (CAS CATO-C4X-160810)
- Demeclocycline Hydrochloride EP Impurity D (CAS 81181-91-1)
- Demeclocycline impurity 12 (CAS CATO-C4X-160812)
- Demeclocycline EP Impurity A (CAS 987-02-0)
- Demeclocycline EP Impurity C (CAS 129044-45-7)
- Demeclocycline EP Impurity F (CAS CATO-C4X-16086)
- Demeclocycline EP Impurity G (CAS 22688-73-9)
- Demeclocycline EP Impurity B (CAS 14206-59-8)
Recommended Standards
- Celecoxib Impurity 65 (CAS CATO-C4X-104365)
- Warfarin impurity 11 (CAS CATO-C4X-17811)
- Celecoxib Impurity 51 (CAS CATO-C4X-104351)
- Picropodopyllotoxone (CAS 477-48-5)
- Vonoprazan Fumarate Impurity 207 (CAS CATO-C4X-1020207)
- Nebivolol Impurity 36 (CAS 129101-33-3)
- Nemonoxacin Impurity 2 (CAS 2770004-81-2)
- (S)-1-Cyclopentylethanamine HCl (CAS 150852-73-6)
- 1,3-Dimethylnaphthalen-2-ol (CAS 106949-25-1)
- (±)-9,10-Dihydrojasmonic Acid (CAS 3572-64-3)
- 2-(4-Methoxyphenyl)-4-oxo-4H-chromen-3-yl 4-methoxybenzenesulfonate (CAS 301193-65-7)
- Urapidil Impurity 9 (CAS 108997-11-1)
- 3-Ethyl 2-methyl 6-hydroxy-3,4-dihydroisoquinoline-2,3(1H)-dicarboxylate (CAS 134388-88-8)
- Des-Gly34-Tirzepatide (CAS CATO-CPTD788940)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com