Demeclocycline EP Impurity A CAS 987-02-0

Purity >90%In StockPharmacopoeial Impurity Standards
CAS No.987-02-0
Molecular FormulaC21H22N2O8
Molecular Weight430.41 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Demeclocycline EP Impurity A CAS 987-02-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 430.41 g/mol gives Demeclocycline EP Impurity A distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Demeclocycline EP Impurity A (CAS 987-02-0), a pharmacopoeial impurity reference standard (molecular formula C21H22N2O8, MW 430.41 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Demeclocycline EP Impurity A (C21H22N2O8) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Demeclocycline EP Impurity A under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC21H22N2O8
Molecular Weight430.41 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>90%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Nitrogen Atoms2

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