Cloperastine impurity 8 CAS 132301-89-4
| CAS No. | 132301-89-4 |
| Molecular Formula | C20H24ClNO |
| Molecular Weight | 329.86 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Cloperastine impurity 8 (CAS 132301-89-4), a pharmacopoeial impurity reference standard (molecular formula C20H24ClNO, MW 329.86 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Cloperastine impurity 8 (C20H24ClNO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 329.86 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Cloperastine impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H24ClNO |
| Molecular Weight | 329.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Cloperastine Standards
- (R)-Cloperastine (CAS 132301-91-8)
- Cloperastine (CAS 3703-76-2)
- Cloperastine Impurity 1 (CAS 5630-78-4)
- Cloperastine Impurity 2 (CAS 4960-10-5)
- Cloperastine Impurity 5 (CAS 75842-85-2)
- Cloperastine Impurity 3 (CAS 6954-45-6)
- Cloperastine Hydrochloride (CAS 14984-68-0)
- (S)-Cloperastine Fendizoate (Levocloperastine Fendizoate) (CAS 220329-19-1)
Recommended Standards
- Clemastine Impurity 23 (CAS CATO-C4X-183723)
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- 2-(2-Aminobutan-2-yl)-6-(trifluoromethyl)pyrimidin-4(3H)-one hydrochloride (CAS 1354951-98-6)
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- (+)-Tianeptine Monosodium Salt (CAS 169293-32-7)
- 3-(4-Aminophenoxy)-N,N-dimethylpropanamide (CAS 1183382-59-3)
- Fragment-[9-31]-Semaglutide (CAS CATO-C4X-2226181)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com