Avacopan CAS 1346623-17-3

Description

Compared with other compounds in its class, the molecular weight of 581.64 g/mol gives Avacopan distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Avacopan (CAS 1346623-17-3), a certified reference material (molecular formula C33H35F4N3O2, MW 581.64 g/mol) for analytical method development and quality control.

The molecular framework of Avacopan (C33H35F4N3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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