Avacopan Impurity 12 CAS CATO-C4X-294512
| CAS No. | CATO-C4X-294512 |
| Molecular Formula | C33H35F4N3O2 |
| Molecular Weight | 581.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Avacopan Impurity 12 (CAS CATO-C4X-294512), a pharmacopoeial impurity reference standard (molecular formula C33H35F4N3O2, MW 581.64 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C33H35F4N3O2, Avacopan Impurity 12 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 581.64 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Avacopan Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C33H35F4N3O2 |
| Molecular Weight | 581.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Avacopan Standards
- Avacopan (CAS 1346623-17-3)
- Avacopan impurity 7 (CAS 1257868-45-3)
- Avacopan Impurity 9 (CAS CATO-C4X-29459)
- Avacopan Impurity 1 (CAS CATO-C4X-29451)
- Avacopan Impurity 10 (CAS CATO-C4X-294510)
- Avacopan Impurity 8 (CAS CATO-C4X-29458)
- Avacopan Impurity 4 (CAS 1346623-05-9)
- Avacopan Impurity 5 (CAS 1346623-09-3)
Recommended Standards
- Alogliptin Impurity 7-d3 (CAS 1268836-55-0（unlabelled）)
- 4-amino-1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]tetrahydrofuran-2-yl]-5-iodo-pyrimidin-2-one (CAS 478843-96-8)
- tert-Butyl 1-((2-acetoxy-2-phenylacetoxy)methyl)-5-(benzyloxy)-1H-benzo[e]indole-3(2H)-carboxylate (CAS 128228-77-3)
- 4-[(3aR,8aR)-Tetrahydro-2,2-dimethyl-4,4,8,8-tetraphenyl-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl]morpholine (CAS 905727-05-1)
- Canagliflozin Impurity 4 (CAS CATO-C4X-11234)
- Glycyrrhizic Acid Impurity 21 (CAS CATO-C4X-253721)
- Lurbinectedin Impurity 20 (CAS 2248127-78-6)
- 3-Bromo-6-chloro-1-methyl-1H-pyrrolo[3,2-b]pyridine (CAS 1620098-37-4)
- 3-Bromo-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-amine (CAS 1781659-18-4)
- 825-51-4 trans-Decahydro-2-naphthol 2-Naphthalenol, decahydro- 2-Naphthol, decahydro- (8CI) 1-06-00-00044 (Beilstein Handbook Reference) AI3-05918 BRN 0773927 Decahydro-beta-naphthol Decahydronaphthol-2 Decahydronapthol-2 2-Decalinol 2-Decalol EINECS 212-545-3 2-Hydroxydecalin Naphthalen-2-ol, decahydro- NSC 2332 NSC 71562 NSC 84186 (CAS 825-51-4)
- 6-Styryl-2-[3-(trifluoromethyl)benzyl]-4,5-dihydro-3(2H)-pyridazinone (CAS 303146-66-9)
- Tert-butyl ((4-(2-methoxyphenyl)piperidin-4-yl)methyl)carbamate (CAS 1158750-87-8)
- (4R)-N,1-dimethylazepan-4-amine (CAS 2165962-73-0)
- Semaglutide impurity 229 (CAS CATO-C4X-2226229)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com