Desvenlafaxine USP Related Compound B CAS 135308-74-6
| CAS No. | 135308-74-6 |
| Molecular Formula | C15H23NO2 |
| Molecular Weight | 249.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 249.35 g/mol gives Desvenlafaxine USP Related Compound B distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Desvenlafaxine USP Related Compound B (CAS 135308-74-6) is a certified pharmaceutical impurity reference standard with the molecular formula C15H23NO2 and a molecular weight of 249.35 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Desvenlafaxine USP Related Compound B is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 249.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Desvenlafaxine USP Related Compound B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H23NO2 |
| Molecular Weight | 249.35 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 1 |
Related Desvenlafaxine Standards
- Desvenlafaxine USP Related Compound A (CAS 1346600-38-1)
- Desvenlafaxine Impurity 2 (CAS CATO-C4X-16102)
- Desvenlafaxine Impurity 1 (CAS CATO-C4X-16101)
- Desvenlafaxine R-Isomer (CAS 142761-11-3)
- Desvenlafaxine S-Isomer (CAS 142761-12-4)
- Desvenlafaxine (CAS 93413-62-8)
- Desvenlafaxine Impurity 3 (CAS CATO-C4X-16103)
- Desvenlafaxine Impurity 4 (CAS CATO-C4X-16104)
Recommended Standards
- Metoprolol Impurity 47 (CAS CATO-C4X-136747)
- Tramadol EP Impurity D ( and Enantiomer) (CAS 80456-81-1)
- Bazedoxifene Acetate Impurity 1 (CAS 223251-16-9)
- Parecoxib Impurity 72 (CAS CATO-C4X-159172)
- Gadobutrol Impurity 119 (CAS CATO-C4X-2120119)
- Prostaglandin Impurity 23 (CAS CATO-C4X-199623)
- Pitolisant impurity 18 (CAS CATO-C4X-252018)
- N1-((4-(4-Isopropoxyphenyl)-1H-pyrrol-3-yl)methyl)-N1-methylethane-1,2-diamine trihydrochloride (CAS 2108631-19-0)
- 2-Chloro-N-(4,6-dimethyl-isoxazolo[5,4-b]pyridin-3-yl)-acetamide (CAS 1171935-26-4)
- 2-Benzyl-2H-spiro[benzo[d]isothiazole-3,3'-pyrrolidine] 1,1-dioxide (CAS 1422137-41-4)
- 4,6-Dibromo-5-hydroxybenzo[d][1,3]oxathiol-2-one (CAS 7735-61-7)
- 2-Chloro-1-[4-(3-chloro-4-fluorobenzenesulfonyl)piperazin-1-yl]ethan-1-one (CAS 923780-46-5)
- Benzyl 3-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-3-yl]-2,3-dihydroindole-1-carboxylate (CAS 1160248-34-9)
- Liraglutide Impurity 28 (CAS CATO-C4X-199228)
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