Pranlukast Impurity 11 CAS 136450-05-0
| CAS No. | 136450-05-0 |
| Molecular Formula | C18H20O3 |
| Molecular Weight | 284.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Pranlukast Impurity 11.
Pranlukast Impurity 11 (CAS 136450-05-0) is a certified pharmaceutical impurity reference standard with the molecular formula C18H20O3 and a molecular weight of 284.35 g/mol.
Structurally, Pranlukast Impurity 11 (C18H20O3) contains a steroid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 284.35 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H20O3 |
| Molecular Weight | 284.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
Related Pranlukast Standards
- Pranlukast impurity 12 (CAS CATO-C4X-180412)
- Pranlukast Impurity 10 (CAS CATO-C4X-180410)
- Pranlukast Impurity 8 (CAS CATO-C4X-18048)
- Pranlukast Impurity 5 (CAS CATO-C4X-18045)
- Pranlukast Impurity 7 (CAS CATO-C4X-18047)
- Pranlukast Impurity 3 (CAS 70977-72-9)
- Pranlukast Impurity N1 (CAS 136450-11-8)
- Pranlukast Impurity 1 (CAS 136450-10-7)
Recommended Standards
- Tolterodine Impurity 7 (CAS 2514856-06-3)
- Nebivolol Impurity 67 (CAS CATO-C4X-196867)
- Tolterodine impurity 34 (CAS CATO-C4X-176734)
- Nebivolol Impurity 70 (CAS CATO-C4X-196870)
- Cyproheptadine impurity 15 (CAS 101596-48-9)
- Ceftriaxone Impurity 39 (CAS 139-33-3(Anhydrate CAS))
- Doxorubicin Dimer Impurity 23 (CAS 201278-93-5)
- Sertraline Impurity 35 (CAS 1808266-64-9 (free base))
- 2-Amino-5-chloro-N-isopropylbenzamide (CAS 926235-02-1)
- 5-Phenyl-N-(thiophen-3-ylmethyl)isoxazole-3-carboxamide (CAS 1207051-81-7)
- Methyl (6-bromopyrimidin-4-yl)carbamate (CAS 1209459-31-3)
- Naltrexone Impurity 68 (CAS 207732-98-7)
- 1-(3-(4-Fluoro-3-methylphenyl)-1,2,4-oxadiazol-5-yl)ethan-1-amine (CAS 1179139-16-2)
- Hexapeptide-10 (CAS 146439-94-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com