Nebivolol Impurity 70 CAS CATO-C4X-196870
| CAS No. | CATO-C4X-196870 |
| Molecular Formula | C14H17FO3S |
| Molecular Weight | 284.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Nebivolol Impurity 70 (CAS CATO-C4X-196870), a pharmacopoeial impurity reference standard (molecular formula C14H17FO3S, MW 284.35 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Nebivolol Impurity 70 (C14H17FO3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H17FO3S |
| Molecular Weight | 284.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Nebivolol Standards
- Nebivolol Impurity 67 (CAS CATO-C4X-196867)
- Nebivolol Impurity 75 (CAS CATO-C4X-196875)
- Nebivolol Impurity 54 (CAS CATO-C4X-196854)
- Nebivolol Impurity 55 (CAS CATO-C4X-196855)
- Nebivolol Impurity 14 (CAS 129050-29-9)
- Nebivolol Impurity 15 (CAS 1029684-20-5)
- Nebivolol Impurity 64 (CAS CATO-C4X-196864)
- Nebivolol Impurity 65 (CAS CATO-C4X-196865)
Recommended Standards
- Pranlukast Impurity 11 (CAS 136450-05-0)
- Artemisinin Impurity 11 (CAS 81496-81-3)
- Tolterodine Impurity 7 (CAS 2514856-06-3)
- Tropicamide (CAS 1508-75-4)
- Minoxidil Impurity 71 (CAS CATO-C4X-170071)
- Lenvatinib Impurity 58 (CAS CATO-C4X-114058)
- Sitagliptin Impurity 69 (CAS CATO-C4X-114469)
- 5-Thioxo-4,5-dihydro-1,3,4-oxadiazole-2-carboxylic acid (CAS 64007-52-9)
- 1-Bromo-3-(cyclopropylmethyl)-5-methylbenzene (CAS 1369877-39-3)
- 3-Chloroisoquinoline-4-carboxylic acid (CAS 123695-38-5)
- 9-((1-Methyl-1H-pyrazol-4-yl)sulfonyl)-1,5-dioxa-9-azaspiro[5.5]undecane (CAS 1797296-13-9)
- N1,N1'-(1,4-Phenylenebis(methanylylidene))bis(N4-phenylbenzene-1,4-diamine) (CAS 57400-99-4)
- N-(4-Bromo-3-methylphenyl)-3-chlorobenzamide (CAS 346698-34-8)
- Semaglutide impurity 26 (CAS CATO-C4X-222626)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com