Nebivolol Impurity 67 CAS CATO-C4X-196867
| CAS No. | CATO-C4X-196867 |
| Molecular Formula | C14H17FO3S |
| Molecular Weight | 284.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Nebivolol Impurity 67 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Nebivolol Impurity 67 (CAS CATO-C4X-196867), a pharmacopoeial impurity reference standard (molecular formula C14H17FO3S, MW 284.35 g/mol) used for the identification and quantification of trace impurities in APIs.
Nebivolol Impurity 67 (C14H17FO3S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C14H17FO3S |
| Molecular Weight | 284.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Nebivolol Standards
- Nebivolol Impurity 70 (CAS CATO-C4X-196870)
- Nebivolol Impurity 75 (CAS CATO-C4X-196875)
- Nebivolol Impurity 54 (CAS CATO-C4X-196854)
- Nebivolol Impurity 55 (CAS CATO-C4X-196855)
- Nebivolol Impurity 14 (CAS 129050-29-9)
- Nebivolol Impurity 15 (CAS 1029684-20-5)
- Nebivolol Impurity 64 (CAS CATO-C4X-196864)
- Nebivolol Impurity 65 (CAS CATO-C4X-196865)
Recommended Standards
- Pranlukast Impurity 11 (CAS 136450-05-0)
- Tolterodine Impurity 7 (CAS 2514856-06-3)
- Tolterodine impurity 34 (CAS CATO-C4X-176734)
- Artemisinin Impurity 11 (CAS 81496-81-3)
- Tocopherol Impurity 41 (CAS 389845-92-5)
- Tedizolid Impurity 64 (CAS 65031-96-1)
- Indapamide Impurity 29 (CAS CATO-C4X-140029)
- 2-methyl-4H,5H,6H-cyclopenta[b]thiophen-4-amine (CAS 1513420-35-3)
- Ethyl 3-(3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl)benzoate (CAS 823195-12-6)
- Benzyl tert-butyl (4-hydroxybutane-1,2-diyl)dicarbamate (CAS 1823478-90-5)
- Methyl (S)-2-(trifluoromethyl)pyrrolidine-2-carboxylate hydrochloride (CAS 1923203-84-2)
- Methyl 5-(2-aminothiazol-4-yl)-2-hydroxybenzoate (CAS 380843-11-8)
- 2-(4-Methoxyphenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic Acid (CAS 956296-81-4)
- Semaglutide impurity 109 (CAS CATO-C4X-2226109)
Why CATO?
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