Lusutrombopag Impurity 75 CAS CATO-C4X-208475
| CAS No. | CATO-C4X-208475 |
| Molecular Formula | C8H4Cl2O3 |
| Molecular Weight | 219.02 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Lusutrombopag Impurity 75 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Lusutrombopag Impurity 75 (CAS CATO-C4X-208475, C8H4Cl2O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Lusutrombopag Impurity 75 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 219.02 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H4Cl2O3 |
| Molecular Weight | 219.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Lusutrombopag Standards
- Lusutrombopag Impurity 42 (CAS 1367365-00-1)
- Lusutrombopag Impurity 44 (CAS 2126856-49-1)
- Lusutrombopag Impurity 73 (CAS CATO-C4X-208473)
- Lusutrombopag Impurity 74 (CAS CATO-C4X-208474)
- Lusutrombopag Impurity 76 (CAS CATO-C4X-208476)
- Lusutrombopag Impurity N2 (CAS 89894-53-1)
- Lusutrombopag Impurity 4 (CAS CATO-C4X-20844)
- Lusutrombopag Impurity N5 (CAS 29841-69-8)
Recommended Standards
- 3-Iodoaniline (CAS 626-01-7)
- (1-(N,N-Dimethylsulfamoyl)-1H-pyrazol-4-yl)boronic acid (CAS 1036990-41-6)
- 1-[(E)-2-bromovinyl]-3,5-difluorobenzene (CAS 1260683-99-5)
- 2-iodanyl-3-methyl-pyridine 2-iodo-3-methylpyridine 22282-58-2 A816084 (CAS 22282-58-2)
- Axitinib Impurity 82 (CAS CATO-C4X-107182)
- Lifitegrast Impurity 142 (CAS 2098810-32-1)
- Baclofen Impurity 41 (CAS 159156-84-0)
- 3-Chloro-1-(chloromethyl)-5-methyl-1H-pyrazole (CAS 51355-86-3)
- Sar-[D-Phe8]-des-Arg9-Bradykinin (CAS 126959-88-4)
- 1-(4-hydroxyquinolin-6-yl)ethan-1-one (CAS 15900-88-6)
- 2-(5-Fluoro-2-methyl-1H-inden-3-yl)acetamide (CAS 1956356-27-6)
- Methyl 4-chloro-3-cyanobenzoate (CAS 181282-80-4)
- exo-IWR-1 (CAS 1127442-87-8)
- Semaglutide Impurity 3 (CAS CATO-C4X-22263)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com