Lusutrombopag Impurity N2 CAS 89894-53-1
| CAS No. | 89894-53-1 |
| Molecular Formula | C8H6Cl2O3 |
| Molecular Weight | 221.04 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lusutrombopag Impurity N2.
Lusutrombopag Impurity N2 (CAS 89894-53-1) is a certified pharmaceutical impurity reference standard with the molecular formula C8H6Cl2O3 and a molecular weight of 221.04 g/mol.
Structurally, Lusutrombopag Impurity N2 (C8H6Cl2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 221.04 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Lusutrombopag Impurity N2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6Cl2O3 |
| Molecular Weight | 221.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
Related Lusutrombopag Standards
- Lusutrombopag Impurity 4 (CAS CATO-C4X-20844)
- Lusutrombopag Impurity 42 (CAS 1367365-00-1)
- Lusutrombopag Impurity 44 (CAS 2126856-49-1)
- Lusutrombopag Impurity 73 (CAS CATO-C4X-208473)
- Lusutrombopag Impurity 74 (CAS CATO-C4X-208474)
- Lusutrombopag Impurity 75 (CAS CATO-C4X-208475)
- Lusutrombopag Impurity 76 (CAS CATO-C4X-208476)
- Lusutrombopag Impurity N5 (CAS 29841-69-8)
Recommended Standards
- 3,5-D (CAS 587-64-4)
- 3,5-dichloro-4-hydrazinylbenzoic acid (CAS 887577-44-8)
- 2-Cyclohexylidene-butyronitrile (CAS 53153-77-8)
- 3,5-Dichloro-4-hydroxybenzohydrazide (CAS 23964-29-6)
- Atogepant Impurity 18 (CAS CATO-C4X-328518)
- Rufinamide USP Related Compound B (CAS 217448-86-7)
- Famotidine Impurity 27 (CAS 1378820-83-7)
- 1-BRomo-2-(2-ethoxyethoxy)benzene (CAS 279262-55-4)
- 1-[(1-ethyl-3-methyl-1h-pyrazol-4-yl)methyl]-3,5-dimethyl-1h-pyrazol-4-amine (CAS 1004643-60-0)
- Des-Ser39-Tirzepatide (CAS CATO-CPTD788936)
- Triarylsulfonium hexafluoroantimonate mixture (CAS 109037-75-4)
- Methyl 2-(2-(3,5-dichlorophenyl)-5-methyl-3-oxo-2,3-dihydro-1H-pyrazol-4-yl)acetate (CAS 477711-21-0)
- 4H-1-benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(2R,3S)-2-(Hydroxymethyl)-1-methyl-3-pyrrolidinyl]-, rel- (CAS 647019-54-3)
- Semaglutide Impurity 16 (CAS CATO-C4X-222616)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com