Cyproterone Acetate EP Impurity I CAS 13698-49-2
| CAS No. | 13698-49-2 |
| Molecular Formula | C23H27ClO4 |
| Molecular Weight | 402.91 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Cyproterone Acetate EP Impurity I (CAS 13698-49-2, C23H27ClO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Cyproterone Acetate EP Impurity I (C23H27ClO4) contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Cyproterone Acetate EP Impurity I meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H27ClO4 |
| Molecular Weight | 402.91 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Halogen Content | Cl-containing |
Related Cyproterone Standards
- Cyproterone Acetate EP Impurity J (CAS 15423-97-9)
- Cyproterone Acetate EP Impurity E (CAS 17184-05-3)
- Cyproterone Impurity 5 (CAS 30337-71-4)
- Cyproterone Impurity 8 (CAS CATO-C4X-16018)
- Cyproterone Acetate EP Impurity B (CAS CATO-C4X-16013)
- Cyproterone Acetate (CAS 427-51-0)
- Cyproterone Acetate-D3 (CAS 427-51-0 (non-labelled))
- Cyproterone Acetate EP Impurity A (CAS 2701-50-0)
Recommended Standards
- Cetirizine Impurity 15 (CAS CATO-C4X-158215)
- 4-(4-(2-Chlorophenyl)-2-phenyloxazol-5-yl)-N,N-diethylaniline (CAS 55766-52-4)
- Levocetirizine Impurity 8 (CAS 83881-46-3)
- 2-[(4-Chlorophenyl)sulfanyl]-4-(4-cyclohexylphenyl)-4-oxobutanoic acid (CAS 329703-21-1)
- Clonazepam Impurity 4 (CAS 52130-87-7)
- Prednisolone Impurity 43 (CAS 905-52-2)
- Nintedanib Impurity 185 (CAS 652140-07-3)
- 2-(4-methoxybenzyl)-2-azabicyclo[2.1.0]pentan-3-one (CAS CATO-C3D-262899)
- 1-Chlorohexadecane-d33 (CAS 352431-13-1)
- 2-(Pyrrolidin-1-yl)cyclohexan-1-one (CAS 22003-63-0)
- Clobazam Impurity 3 (CAS CATO-C4X-27523)
- (-)-(1R,3S)-N-Fmoc-β-homocycloleucine (CAS 220497-67-6)
- (S)-2-(Piperidin-2-yl)ethanol ((1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate (CAS 652144-68-8)
- Semaglutide impurity 44 (CAS CATO-C4X-222644)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com