Prednisolone Impurity 43 CAS 905-52-2
| CAS No. | 905-52-2 |
| Molecular Formula | C21H28O5 |
| Molecular Weight | 360.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Prednisolone Impurity 43 (C21H28O5) contains a flavonoid core, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Prednisolone Impurity 43 (CAS 905-52-2, C21H28O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Prednisolone Impurity 43 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H28O5 |
| Molecular Weight | 360.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Prednisolone Standards
- Prednisolone Impurity 37 (CAS 307518-72-5)
- Prednisolone EP Impurity F (CAS 600-90-8)
- Prednisolone impurity 65 (CAS 20380-15-8)
- Prednisolone Impurity 44 (CAS 7055-53-0)
- Prednisolone EP Impurity H (CAS 2427-64-7)
- Prednisolone 20alpha-Hydroxy Impurity (CAS 15847-24-2)
- Prednisolone EP Impurity G (CAS 2299-46-9)
- Prednisolone impurity 55 (CAS CATO-C4X-173755)
Recommended Standards
- Prednisone Impurity 16 (CAS 15714-29-1)
- Hydrocortisone EP Impurity G (CAS 14760-49-7)
- 17-Hydroxy-Methylprednisolone Impurity E Derivative (CAS 167997-11-7)
- Hydrocortisone EP Impurity E (CAS 600-99-7)
- Alectinib impurity 22 (CAS CATO-C4X-283622)
- Arginine Impurity 18 (CAS CATO-C4X-242418)
- Oseltamivir Impurity 87 HCI (CAS CATO-C4X-172087)
- Benzo[d]isothiazole-6-carbonitrile (CAS 1015069-66-5)
- 7-Benzyl-1H-indole (CAS 3377-78-4)
- Oxyvanadium phthalocyanine (CAS 13930-88-6)
- (4-(Cyclopropylsulfonyl)phenyl)boronic acid (CAS 1217501-07-9)
- tert-Butyl (2,2,2-trifluoroacetyl)carbamate (CAS 81464-59-7)
- Tiagabine Related Compound A (F0E177) (CAS 145821-60-9)
- D-[Ala]24-Semaglutide (CAS CATO-C4X-2226126)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com