Rimegepant Impurity 137 CAS 1373116-08-5
| CAS No. | 1373116-08-5 |
| Molecular Formula | C10H16N4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Rimegepant Impurity 137 (CAS 1373116-08-5, C10H16N4HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, Rimegepant Impurity 137 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 228.72 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures Rimegepant Impurity 137 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H16N4 2*HCl |
| Molecular Weight | 228.72 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Rimegepant Standards
- Rimegepant Impurity 63 (CAS 1071154-76-1)
- Rimegepant Impurity 102 (CAS 1146515-11-8)
- Rimegepant Impurity 61 (CAS 1190363-43-9)
- Rimegepant Impurity 9 (CAS 1190363-46-2)
- Rimegepant Impurity 59 (CAS 1190363-47-3)
- Rimegepant Impurity 17 (CAS 1190363-50-8)
- Rimegepant (CAS 1289023-67-1)
- Rimegepant Impurity 51 (CAS 1289023-89-7)
Recommended Standards
- Repaglinide Impurity 29 (CAS CATO-C4X-118629)
- Bupivacaine EP Impurity C (CAS 1797894-80-4)
- Bumetanide Impurity 5 (CAS 22892-96-2)
- 3-((((6-Methylpyridin-3-yl)methyl)amino)methyl)benzonitrile (CAS 1240946-95-5)
- AG-1557 (CAS 189290-58-2)
- (1R,2R)-1-Amino-2-phenylcyclopropane-1-carboxylic acid (CAS 129101-41-3)
- 4-(2-ethoxyethoxy)benzene-1-sulfonyl chloride (CAS 264624-20-6)
- Edaravone Impurity 52 (CAS CATO-C4X-106252)
- Galanthamine Impurity 31 (CAS CATO-C4X-143531)
- Tetrapeptide-30/Tegopep (CAS 1036207-61-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com