Promethazine N-β-D-Glucuronide CAS 137908-81-7
| CAS No. | 137908-81-7 |
| Molecular Formula | C23H28N2O6S |
| Molecular Weight | 460.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Promethazine N-β-D-Glucuronide (C23H28N2O6S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Promethazine N-β-D-Glucuronide (CAS 137908-81-7) is a high-purity analytical reference standard with the molecular formula C23H28N2O6S and a molecular weight of 460.54 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H28N2O6S |
| Molecular Weight | 460.54 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Promethazine Standards
- Promethazine Impurity 49 (CAS CATO-C4X-141849)
- Promethazine Impurity 54 (CAS CATO-C4X-141854)
- Promethazine Impurity 46 (CAS CATO-C4X-141846)
- Promethazine Impurity 50 (CAS CATO-C4X-141850)
- Promethazine Impurity 47 (CAS CATO-C4X-141847)
- Promethazine Impurity 66 (CAS CATO-C4X-141866)
- Promethazine Impurity 67 (CAS 7647-63-4)
- Promethazine Impurity 37 (CAS CATO-C4X-141837)
Recommended Standards
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- Fluorometholone Impurity 11 (CAS CATO-C4X-193311)
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- 898771-24-9 (2-Chlorophenyl)(thiophen-3-yl)methanone DTXSID40591669 (CAS 898771-24-9)
- 5,8-Difluoro-4-hydroxyquinoline-3-carbonitrile (CAS 61338-33-8)
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