Promethazine Impurity 49 CAS CATO-C4X-141849
| CAS No. | CATO-C4X-141849 |
| Molecular Formula | C28H25N3S2 |
| Molecular Weight | 467.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C28H25N3S2, Promethazine Impurity 49 contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 467.65 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Promethazine Impurity 49 (CAS CATO-C4X-141849, C28H25N3S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Promethazine Impurity 49 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H25N3S2 |
| Molecular Weight | 467.65 g/mol |
| Purity | ＞95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Promethazine Standards
- Promethazine N-β-D-Glucuronide (CAS 137908-81-7)
- Promethazine Impurity 54 (CAS CATO-C4X-141854)
- Promethazine Impurity 46 (CAS CATO-C4X-141846)
- Promethazine Impurity 50 (CAS CATO-C4X-141850)
- Promethazine Impurity 47 (CAS CATO-C4X-141847)
- Promethazine Impurity 66 (CAS CATO-C4X-141866)
- Promethazine Impurity 67 (CAS 7647-63-4)
- Promethazine Impurity 48 (CAS CATO-C4X-141848)
Recommended Standards
- 2-(1,4'-Bipiperidin)-1'-yl-N-cycloheptyl-6,7-dimethoxy-4-quinazolinamine trihydrochloride hydrate 864289-85-0 DH-0071 (CAS 864289-85-0)
- N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-(2,6-dichlorophenyl)-N'-methyl-4,5-dihydroisoxazole-5-carbohydrazide (CAS 338774-96-2)
- N-Boc-(1S)-3-[3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-exo-8-azabicyclo[3.2.1]oct-8-yl]-1-phenyl-1-propanamine (CAS 376348-70-8)
- 2-((2,5-Dimethylbenzyl)thio)-6,7-dimethoxy-3-octylquinazolin-4(3H)-imine (CAS 860789-66-8)
- Loratadine Impurity 25 (CAS CATO-C4X-142625)
- Ropivacaine Impurity 40 (CAS CATO-C4X-175340)
- Ceritinib Impurity 56 (CAS CATO-C4X-104856)
- Eltrombopag Impurity 53 (CAS CATO-C4X-119853)
- 1-(2-Chloropyridin-4-yl)butan-1-one (CAS 113961-70-9)
- 2-Amino-N-(5-propyl-1,3,4-thiadiazol-2-yl)acetamide (CAS 1175836-99-3)
- 3-Phenyl-2-propyl-2H-azirine (CAS 92971-90-9)
- 1,1’-[(1S,2S)-Cyclohexane-1,2-diyl]bis[3-[3,5-bis(trifluoromethyl)phenyl]thiourea] (CAS 1140969-69-2)
- 2-(5-(4-Fluorophenyl)furan-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1396753-07-3)
- Fibrinopeptide A (human) (CAS 25422-31-5)
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