Levofloxacin Hemihydrate CAS 138199-71-0
| CAS No. | 138199-71-0 |
| Molecular Formula | 2*C18H20FN3O4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Levofloxacin Hemihydrate is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Levofloxacin Hemihydrate (CAS 138199-71-0) is a high-purity analytical reference standard with the molecular formula C18H20FN3O4H2O and a molecular weight of 379.39 g/mol.
The molecular framework of Levofloxacin Hemihydrate (C18H20FN3O4H2O) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Levofloxacin Hemihydrate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | 2*C18H20FN3O4 H2O |
| Molecular Weight | 379.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Levofloxacin Standards
- Levofloxacin (CAS 100986-85-4)
- Levofloxacin R-Isomer（Levofloxacin EP Impurity A） (CAS 100986-86-5)
- Levofloxacin EP Impurity F (CAS 100986-89-8)
- Levofloxacin Impurity 35 (CAS 1012310-27-8)
- Levofloxacin Impurity 51 (CAS 1026952-91-9)
- Levofloxacin Impurity N27 (CAS 1036016-10-0)
- Levofloxacin Impurity 100 (CAS 104600-15-9)
- Levofloxacin Impurity 101 (CAS 105804-40-8)
Recommended Standards
- 4-(4-Butoxybenzoyl)-5-(4-chlorophenyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one (CAS 609795-77-9)
- 6-Chloro-7-cyclopropyl-[1,2,4]triazolo[4,3-b]pyridazin-3-amine (CAS 1178583-40-8)
- 2-((4-Ethyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(naphthalen-1-yl)acetamide (CAS 618427-40-0)
- 2-Ethylbenzofuran-6-amine (CAS 27408-35-1)
- 4-(3,4-Dichlorophenyl)-5-[3-(dimethylamino)phenyl]-4h-1,2,4-triazole-3-thiol (CAS 796067-57-7)
- N-((3-(allylcarbamoyl)-4,5-dihydroisoxazol-5-yl)methyl)-3-(2-chlorophenyl)-5-methylisoxazole-4-carboxamide (CAS 321432-38-6)
- 2-(Phenoxymethyl)thiazole-4-carbaldehyde (CAS 1082576-04-2)
- tert-butyl N-(trimethylsilyl)carbamate (CAS 238096-95-2)
- 3-Bromo-5-(3-chlorophenyl)-1H-1,2,4-triazole (CAS 1374407-78-9)
- ((Cys31,Nva34)-Neuropeptide Y (27-36))2 (CAS 172997-92-1)
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